Low-dose neuroleptic therapy and extrapyramidal side effects in schizophrenia: An effect size analysis.

نویسندگان

  • C Barbui
  • B Saraceno
چکیده

A meta-analysis of the published literature was performed in order to quantify the efficacy of low-dose neuroleptic therapy in reducing extrapyramidal side effects in schizophrenic patients. A low-dose regimen between 50-100 mg equivalents of chlorpromazine, in comparison to a standard-dose regimen between 200-500 mg reduced extrapyramidal side effects by a 0.30 (+/-0.12) standard deviation, which is only a limited effect.

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عنوان ژورنال:
  • European psychiatry : the journal of the Association of European Psychiatrists

دوره 11 8  شماره 

صفحات  -

تاریخ انتشار 1996